Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

Published:2017-07-14 Issue:8 Volume:7 Page:5316-5320
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

He Congfa¹,Hou Mengqing¹,Zhu Zixi¹,Gu Zhenhua¹^ORCID

Affiliation:

1. Department of Chemistry and Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, P. R. China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.7b01855

Reference61 articles.

1. A twist of nature – the significance of atropisomers in biological systems

2. Atroposelective Synthesis of Axially Chiral Biaryl Compounds

3. Atropisomers and near-atropisomers: achieving stereoselectivity by exploiting the conformational preferences of aromatic amides

4. Biological Stereoselectivity of Atropisomeric Natural Products and Drugs

5. The Challenge of Atropisomerism in Drug Discovery

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