General and Practical Route to Diverse 1-(Difluoro)alkyl-3-aryl Bicyclo[1.1.1]pentanes Enabled by an Fe-Catalyzed Multicomponent Radical Cross-Coupling Reaction-Reference-Cited by-同舟云学术

General and Practical Route to Diverse 1-(Difluoro)alkyl-3-aryl Bicyclo[1.1.1]pentanes Enabled by an Fe-Catalyzed Multicomponent Radical Cross-Coupling Reaction

Published:2022-09-08 Issue:19 Volume:12 Page:11547-11556
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Rentería-Gómez Angel¹,Lee Wes²,Yin Shuai¹,Davis Michael²,Gogoi Achyut Ranjan¹^ORCID,Gutierrez Osvaldo¹²^ORCID

Affiliation:

1. Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States

2. Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, United States

Funder

Division of Chemistry

Welch Foundation

Camille and Henry Dreyfus Foundation

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.2c03498

Reference52 articles.

1. Saturated bioisosteres of benzene: where to go next?

2. Nonconjugated Hydrocarbons as Rigid‐Linear Motifs: Isosteres for Material Sciences and Bioorganic and Medicinal Chemistry

3. (S)-(+)-2-(3‘-Carboxybicyclo[1.1.1]pentyl)- glycine, a Structurally New Group I Metabotropic Glutamate Receptor Antagonist

4. Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

5. Evaluation oftert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

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