Synthesis of Esomeprazole and Related Proton Pump Inhibitors through Iron-Catalyzed Enantioselective Sulfoxidation

Author:

Nishiguchi Shigenobu1,Izumi Takuhiro1,Kouno Takayoshi2,Sukegawa Junpei1,Ilies Laurean34ORCID,Nakamura Eiichi3ORCID

Affiliation:

1. API Process Research Department, API Business Division, Towa Pharmaceutical Co., Ltd., Amagasaki Research Incubation Center 3F, 7-1-3 Doi-cho, Amagasaki, Hyogo 660-0083, Japan

2. Production Department, Himeji Plant, Daichikasei Co., Ltd., 336-2 Jihoji, Himeji, Hyogo 671-2244, Japan

3. Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

4. RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Center of Innovation Program

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Reference42 articles.

1. a Iron Catalysis in Organic Chemistry; Plietker, B., Ed. Wiley-VCH: Weinheim, 2008; pp 1–279.

2. Low-Valent Iron-Catalyzed C−C Bond Formation−Addition, Substitution, and C−H Bond Activation

3. c The Chemistry of Organoiron Compounds; Marek, I., Rappoport, Z., Eds. John Wiley & Sons, Ltd.: Chichester, 2014; pp 1–649.

4. Iron Catalysis in Organic Synthesis

5. Iron-Catalyzed Cross-Coupling Reactions

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