Development of a Safe and Environmentally Benign Manufacturing Process for Esomeprazole using an Iron Catalyst and Hydrogen Peroxide

Author:

Nishiguchi Shigenobu1ORCID,Izumi Takuhiro1,Yamada Tatsuya2,Kouno Takayoshi2,Ilies Laurean34ORCID

Affiliation:

1. API Process Research Department, API Business Unit R&D Division, Towa Pharmaceutical Co., Ltd., Amagasaki Research Incubation Center 3F, 7-1-3 Doi-cho, Amagasaki, Hyogo 660-0083, Japan

2. Production Department, Himeji Plant, Daichikasei Co., Ltd., 336-2 Jihoji, Himeji, Hyogo 671-2244, Japan

3. Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

4. RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Publisher

American Chemical Society (ACS)

Reference21 articles.

1. Applications of Catalytic Asymmetric Sulfide Oxidations to the Syntheses of Biologically Active Sulfoxides

2. Asymmetric oxidation of sulfides

3. aLarsson, E. M.; Stenhede, U. J.; Soerensen, H.; Von Unge, P.; Oskar, S.; Cotton, H. K. Process for Synthesis of Substituted Sulphoxides. WO9602535A1, 1996.

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