Uncovering the Relationship between the Change in Heat Capacity for Enzyme Catalysis and Vibrational Frequency through Isotope Effect Studies
Author:
Affiliation:
1. School of Science, Faculty of Science and Engineering, University of Waikato, Hamilton 3240, New Zealand
2. School of Biochemistry, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, United Kingdom
Funder
Engineering and Physical Sciences Research Council
University of Bath
Biotechnology and Biological Sciences Research Council
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.8b01025
Reference57 articles.
1. Mechanism from Isotope Effects
2. Enzymatic transition states and dynamic motion in barrier crossing
3. Protein motions during catalysis by dihydrofolate reductases
4. Unraveling the role of protein dynamics in dihydrofolate reductase catalysis
5. Physical Organic Chemistry
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