Product Deuterium Isotope Effect for Orotidine 5‘-Monophosphate Decarboxylase: Evidence for the Existence of a Short-Lived Carbanion Intermediate
Author:
Affiliation:
1. Department of Chemistry, University at Buffalo, Buffalo, New York 14260, and Departments of Biochemistry and Chemistry, University of Illinois, Urbana, Illinois 61801
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja076222f
Reference19 articles.
1. The structural basis for the remarkable catalytic proficiency of orotidine 5′-monophosphate decarboxylase
2. Enzymatic reactions involving novel mechanisms of carbanion stabilization
3. Catalytic Proficiency: The Unusual Case of OMP Decarboxylase
4. A Proficient Enzyme
5. Activation of Orotidine 5‘-Monophosphate Decarboxylase by Phosphite Dianion: The Whole Substrate is the Sum of Two Parts
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