Fragment-Based Design of Small Molecule X-Linked Inhibitor of Apoptosis Protein Inhibitors-Reference-Cited by-同舟云学术

Fragment-Based Design of Small Molecule X-Linked Inhibitor of Apoptosis Protein Inhibitors

Published:2008-10-29 Issue:22 Volume:51 Page:7111-7118
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Jui-Wen¹,Zhang Ziming¹,Wu Bainan¹,Cellitti Jason F.¹,Zhang Xiyun¹,Dahl Russell¹,Shiau Chung-Wai¹,Welsh Kate¹,Emdadi Aras¹,Stebbins John L.¹,Reed John C.¹,Pellecchia Maurizio¹

Affiliation:

1. Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8006992

Reference45 articles.

1. Controlling the Caspases

2. Cellular, Biochemical, and Genetic Analysis of Mechanism of Small Molecule IAP Inhibitors

3. Mechanism of XIAP-Mediated Inhibition of Caspase-9

4. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

5. Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

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