Use of the Fused NS4A Peptide−NS3 Protease Domain To Study the Importance of the Helicase Domain for Protease Inhibitor Binding to Hepatitis C Virus NS3-NS4A-Reference-Cited by-同舟云学术

Use of the Fused NS4A Peptide−NS3 Protease Domain To Study the Importance of the Helicase Domain for Protease Inhibitor Binding to Hepatitis C Virus NS3-NS4A

Published:2009-01-02 Issue:4 Volume:48 Page:744-753
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Thibeault Diane¹,Massariol Marie-Josée¹,Zhao Songping¹,Welchner Ewald¹,Goudreau Nathalie¹,Gingras Rock¹,Llinàs-Brunet Montse¹,White Peter W.¹

Affiliation:

1. Boehringer Ingelheim (Canada) Ltd., 2100 Cunard Street, Laval, QC, Canada H7S 2G5

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi801931e

Reference50 articles.

1. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites

2. Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus.

3. 2 Blunting the Swiss Army Knife of Hepatitis C Virus: Inhibitors of NS3/4A Protease

4. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

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