Agonists for the Chemokine Receptor CXCR4-Reference-Cited by-同舟云学术

Agonists for the Chemokine Receptor CXCR4

Published:2011-06-15 Issue:8 Volume:2 Page:597-602
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Lefrançois Marilou¹,Lefebvre Marie-Reine¹,Saint-Onge Geneviève²,Boulais Philip E.¹,Lamothe Simon²³,Leduc Richard¹,Lavigne Pierre¹,Heveker Nikolaus²³,Escher Emanuel¹

Affiliation:

1. Département de Pharmacologie, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada

2. Centre de Recherche, Hôpital Sainte-Justine, Montréal, Québec H3T 1C5, Canada

3. Département de Biochimie, Université de Montréal, Montréal, Québec H3C 3J7, Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml200084n

Reference25 articles.

1. Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

2. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor

3. Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor Fusin/CXCR-4

4. Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1

5. Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles

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