Oxidative Metabolism of Combretastatin A-1 Produces Quinone Intermediates with the Potential To Bind to Nucleophiles and To Enhance Oxidative Stress via Free Radicals-Reference-Cited by-同舟云学术

Oxidative Metabolism of Combretastatin A-1 Produces Quinone Intermediates with the Potential To Bind to Nucleophiles and To Enhance Oxidative Stress via Free Radicals

Published:2007-10-18 Issue:12 Volume:20 Page:1885-1894
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Folkes Lisa K.¹,Christlieb Martin¹,Madej Edyta¹,Stratford Michael R. L.¹,Wardman Peter¹

Affiliation:

1. University of Oxford, Gray Cancer Institute, P.O. Box 100, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx7002195

Reference62 articles.

1. Vascular-targeting therapies for treatment of malignant disease

2. Tumour vascular targeting

3. Pathophysiologic Effects of Vascular-Targeting Agents and the Implications for Combination with Conventional Therapies

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