Identification of a Small Molecule Inhibitor of Importin β Mediated Nuclear Import by Confocal On-Bead Screening of Tagged One-Bead One-Compound Libraries-Reference-Cited by-同舟云学术

Identification of a Small Molecule Inhibitor of Importin β Mediated Nuclear Import by Confocal On-Bead Screening of Tagged One-Bead One-Compound Libraries

Published:2010-08-20 Issue:10 Volume:5 Page:967-979
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Hintersteiner Martin¹,Ambrus Géza²,Bednenko Janna²,Schmied Mario,Knox Andrew J. S.¹,Meisner Nicole-Claudia,Gstach Hubert,Seifert Jan-Marcus,Singer Eric L.²,Gerace Larry²,Auer Manfred¹

Affiliation:

1. The University of Edinburgh, School of Biological Sciences (CSE) and School of Biomedical Sciences (CMVM), CH Waddington Building, 3.07, The King’s Buildings, Mayfield Road, Edinburgh EH9 3JD, U.K.

2. Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb100094k

Reference36 articles.

1. Crossing the Nuclear Envelope: Hierarchical Regulation of Nucleocytoplasmic Transport

2. Molecular mechanism of the nuclear protein import cycle

3. Importins and exportins: how to get in and out of the nucleus

4. Structural Biology of Nucleocytoplasmic Transport

5. Nucleocytoplasmic Transport: Navigating the Channel

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