Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation

Author:

Wu Jiaqi1,Li Zhao2,Liu Xiaofan1,Feng Dongyan3,Liang Ruichao1,Su Xin1,Li Dahong3ORCID,Hua Huiming3ORCID,Cao Hao1ORCID

Affiliation:

1. School of Life Science and Biopharmaceutics and Key Laboratory of Microbial Pharmaceutics, Liaoning Province, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China

2. Central Laboratory, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210000, P. R. China

3. Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, and School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China

Funder

China Postdoctoral Science Foundation

Shenyang Pharmaceutical University

Natural Science Foundation of Liaoning Province

Department of Education of Liaoning Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

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