The Role of Autophagy in the Degradation of Misfolded HLA-B27 Heavy Chains
Author:
Affiliation:
1. National Institute of Arthritis and Musculoskeletal and Skin Diseases; NIH; Bethesda Maryland
2. National Institute of Child Health and Human Development; NIH; Bethesda Maryland
Funder
National Institutes of Health
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Publisher
Wiley
Subject
Immunology,Rheumatology,Immunology and Allergy
Reference48 articles.
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2. HLA-B27;Bowness;Annu Rev Immunol,2015
3. Increased conformational flexibility of HLA-B*27 subtypes associated with ankylosing spondylitis;Loll;Arthritis Rheumatol,2016
4. Misfolding of HLA-B27 as a result of its B pocket suggests a novel mechanism for its role in susceptibility to spondyloarthropathies;Mear;J Immunol,1999
5. HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum;Dangoria;J Biol Chem,2002
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