Urinary Methyleugenol-deoxyadenosine Adduct as a Potential Biomarker of Methyleugenol Exposure in Rats-Reference-Cited by-同舟云学术

Urinary Methyleugenol-deoxyadenosine Adduct as a Potential Biomarker of Methyleugenol Exposure in Rats

Published:2018-01-25 Issue:5 Volume:66 Page:1258-1263
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Feng Yukun¹,Wang Saide¹,Wang Hui¹,Peng Ying¹,Zheng Jiang¹²^ORCID

Affiliation:

1. Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, People’s Republic of China

2. State Key Laboratory of Functions and Applications of Medicinal Plants, Key Laboratory of Pharmaceutics of Guizhou Province and Guizhou Medical University, Guiyang, Guizhou 550004, People’s Republic of China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.7b05186

Reference32 articles.

1. Safety assessment of allylalkoxybenzene derivatives used as flavouring substances — methyl eugenol and estragole

2. Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic

3. Inhibition of methyleugenol bioactivation by the herb-based constituent nevadensin and prediction of possible in vivo consequences using physiologically based kinetic modeling

4. National Toxicology Program (NTP). 14th Report on Carcinogens;NTP:Research Triangle Park, NC, 2016; https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf(accessed Oct 29, 2017) .

5. Cytochrome P450 mediated bioactivation of methyleugenol to 1'- hydroxymethyleugenol in Fischer 344 rat and human liver microsomes

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