Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory (Cichorium intybus L.)

Author:

Cankar Katarina1ORCID,Hakkert Johanna Christina1,Sevenier Robert2,Papastolopoulou Christina1,Schipper Bert1,Baixinho João P.34,Fernández Naiara3,Matos Melanie S.34ORCID,Serra Ana Teresa34,Santos Claudia Nunes345ORCID,Vahabi Khabat6,Tissier Alain67ORCID,Bundock Paul2,Bosch Dirk1

Affiliation:

1. Wageningen Plant Research, Wageningen University & Research, Droevendaalsesteeg 1, 6708PB Wageningen, The Netherlands

2. Keygene N.V., Agro Business Park 90, 6708PW Wageningen, Netherlands

3. Instituto de Biologia Experimental e Tecnológica (iBET), Av. República, Qta. Marquês, 2780-157 Oeiras, Portugal

4. Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB NOVA), Av. da República, 2780-157 Oeiras, Portugal

5. iNOVA4Health, NOVA Medical School Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal

6. Department of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, 06120 Halle (Saale), Germany

7. Martin-Luther-Universität Halle-Wittenberg, Institut für Pharmazie, Kurt-Mothes-Str. 3, 06120 Halle (Saale), Germany

Funder

European Regional Development Fund

H2020 LEIT Biotechnology

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

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