Synthesis of 2-exo-Methylenepenam and 3-Chloro-Δ3-cephem through a Sequential Reductive 1,2-Elimination/S−S Bond Fission or Chloride Ion-Addition/Cyclization of 3,4-Disubstituted 2-Butenoates in Metal Salt/Metal Combinations-Reference-Cited by-同舟云学术

Synthesis of 2-exo-Methylenepenam and 3-Chloro-Δ3-cephem through a Sequential Reductive 1,2-Elimination/S−S Bond Fission or Chloride Ion-Addition/Cyclization of 3,4-Disubstituted 2-Butenoates in Metal Salt/Metal Combinations

Published:1997-05-01 Issue:11 Volume:62 Page:3610-3617
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Tanaka Hideo¹,Sumida Shin-ichi¹,Nishioka Yoichi¹,Kobayashi Noriko¹,Tokumaru Yoshihisa¹,Kameyama Yutaka¹,Torii Sigeru¹

Affiliation:

1. Department of Applied Chemistry, Faculty of Engineering, Okayama University, Tsushima-naka 3-1-1 Okayama, 700 Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo970051n

Reference25 articles.

1. 2-substituted penems, new candidates for cephalosporinase inhibitors

2. A facile synthesis of 2-exo-methylenepenam; a potent intermediate for syntheses of new β-lactamase inhibitors

3. Preparation of 2-exomethylene penam and penicillin-2-carboxylate systems

4. A Facile Synthesis of 2-exo-Methylenepenam Through Reductive Cyclization of Allenecarboxylates in a Metal Salt/Metal Bimetal Redox System

5. Druckhemier, W.; Adam, F.; Fischer, G.; Kirrstetter, R.Advances inDrug Research; Druckhemier, W. Ed.; Academic Press: New York, 1988; Vol. 17, p 190.

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