Detection of Farnesyltransferase Interface Hot Spots through Computational Alanine Scanning Mutagenesis
Author:
Affiliation:
1. REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jp205481y
Reference143 articles.
1. Farnesyltransferase inhibitors: promises and realities
2. Lately, It Occurs to Me What a Long, Strange Trip It's Been for the Farnesyltransferase Inhibitors
3. Inhibition of farnesyltransferase: A rational approach to treat cancer?
4. All ras proteins are polyisoprenylated but only some are palmitoylated
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Characterizing the hotspots involved in RON-MSPβ complex formation using in silico alanine scanning mutagenesis and molecular dynamics simulation;Advanced Pharmaceutical Bulletin;2017-04-13
2. Bridging computational modeling with amino acid replacements to investigate GHS-R1a-peptidomimetic recognition;European Journal of Medicinal Chemistry;2016-11
3. Computational Biochemistry;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2015
4. Discovery of New Sites for Drug Binding to the Hypertension-Related Renin-Angiotensinogen Complex;Chemical Biology & Drug Design;2014-03-18
5. Computational Alanine Scanning Mutagenesis: MM-PBSA vs TI;Journal of Chemical Theory and Computation;2013-02-25
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3