Novel Antiviral C5-Substituted Pyrimidine Acyclic Nucleoside Phosphonates Selected as Human Thymidylate Kinase Substrates-Reference-Cited by-同舟云学术

Novel Antiviral C5-Substituted Pyrimidine Acyclic Nucleoside Phosphonates Selected as Human Thymidylate Kinase Substrates

Published:2010-12-03 Issue:1 Volume:54 Page:222-232
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Topalis Dimitri¹,Pradère Ugo²,Roy Vincent²,Caillat Christophe³,Azzouzi Ahmed²,Broggi Julie²,Snoeck Robert⁴,Andrei Graciela⁴,Lin Jay⁵,Eriksson Staffan⁵,Alexandre Julie A. C.¹,El-Amri Chahrazade¹,Deville-Bonne Dominique¹,Meyer Philippe³,Balzarini Jan⁴,Agrofoglio Luigi A.²

Affiliation:

1. Groupe d’Enzymologie Moléculaire et Fonctionnelle, UR4-UPMC, Université Pierre et Marie Curie, Sorbonne Universités, case courrier 256, 7, quai St Bernard, 75252 Paris Cedex 05, France

2. Institut de Chimie Organique et Analytique, Centre National de Recherche Scientifique Unité Mixte de Recherche 6005, Université d’Orléans, 45067 Orléans, France

3. Laboratoire d’Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique UPR 3082, 91198 Gif-sur-Yvette Cedex, France

4. REGA Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium

5. Department of Veterinary Medical Chemistry, Swedish University of Agricultural Sciences, Box 575, Biomedical Center, S-751 24 Uppsala, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1011462

Reference34 articles.

1. Acyclic nucleoside phosphonates: Past, present and future

2. Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates

3. Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells

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