1,4-Dihydroindeno[1,2-c]pyrazoles with Acetylenic Side Chains as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors with Low Affinity for the hERG Ion Channel-Reference-Cited by-同舟云学术

1,4-Dihydroindeno[1,2-c]pyrazoles with Acetylenic Side Chains as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors with Low Affinity for the hERG Ion Channel

Published:2007-04-11 Issue:9 Volume:50 Page:2011-2029
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dinges Jürgen¹,Albert Daniel H.¹,Arnold Lee D.¹,Ashworth Kimba L.¹,Akritopoulou-Zanze Irini¹,Bousquet Peter F.¹,Bouska Jennifer J.¹,Cunha George A.¹,Davidsen Steven K.¹,Diaz Gilbert J.¹,Djuric Stevan W.¹,Gasiecki Alan F.¹,Gintant Gary A.¹,Gracias Vijaya J.¹,Harris Christopher M.¹,Houseman Kathryn A.¹,Hutchins Charles W.¹,Johnson Eric F.¹,Li Hu¹,Marcotte Patrick A.¹,Martin Ruth L.¹,Michaelides Michael R.¹,Nyein Michelle¹,Sowin Thomas J.¹,Su Zhi¹,Tapang Paul H.¹,Xia Zhiren¹,Zhang Henry Q.¹

Affiliation:

1. Global Pharmaceutical Research and Development, Abbott Laboratories, 200 Abbott Park Road, Abbott Park, Illinois 60064-6217, and Abbott Bioresearch Center, 100 Research Drive, Worcester, Massachusetts 01605-5314

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm061223o

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