Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations-Reference-Cited by-同舟云学术

Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations

Published:2016-11-21 Issue:23 Volume:59 Page:10692-10704
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nocentini Alessio¹²,Ferraroni Marta³,Carta Fabrizio¹,Ceruso Mariangela³,Gratteri Paola²,Lanzi Cecilia⁴,Masini Emanuela⁴,Supuran Claudiu T.¹

Affiliation:

1. Università degli Studi di Firenze, Neurofarba Department., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy

2. Università degli Studi di Firenze, Neurofarba Department., Sezione di Scienze Farmaceutiche, Laboratory of Molecular Modeling Cheminformatics & QSAR, via U. Schiff 6, 50019 Sesto Fiorentino (Florence), Italy

3. Università degli Studi di Firenze, Polo Scientifico, Via della Lastruccia 3, 50019 Sesto Fiorentino (Florence), Italy

4. Università degli Studi di Firenze, Neurofarba Department., Sezione di Farmacologia, Viale Pieraccini 6, 50139 Florence, Italy

Funder

Seventh Framework Programme

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01389

Reference78 articles.

1. Sulfonamides and their isosters as carbonic anhydrase inhibitors