Synthesis and Structure–Activity Relationship Investigation of Adenosine-Containing Inhibitors of Histone Methyltransferase DOT1L
Author:
Affiliation:
1. Department of Pharmacology and §Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm300917h
Reference32 articles.
1. Chromatin Modifications and Their Function
2. Structural and Sequence Motifs of Protein (Histone) Methylation Enzymes
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4. The Epigenomics of Cancer
5. Protein methyltransferases as a target class for drug discovery
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