Treatment of Human Cells with N-Nitroso(acetoxymethyl)methylamine:  Distribution Patterns of Piperidine-Sensitive DNA Damage at the Nucleotide Level of Resolution Are Related to the Sequence Context

Author:

Cloutier Jean-François1,Drouin Régen1,Castonguay Andre1

Affiliation:

1. Laboratory of Cancer Etiology and Chemoprevention, Faculty of Pharmacy, Laval University, Quebec City, Québec G1K 7P4, Canada, and Division of Pathology, Department of Medical Biology, Faculty of Medicine, Laval University, and Unité de recherche en génétique humaine et moléculaire, Research Centre, Pavillon St-François d'Assise, Centre Hospitalier Universitaire de Québec, Québec, Québec, Canada

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference49 articles.

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2. Holmquist, G. P., and Drouin, R. (1998) Cyclobutane dimer frequency and their repair rates drive tumor mutation frequency in p53 genes. InLandmarks in Photobiology(Hönigsmann, H., Knobler, R. M., Trautinger, F., and Jori, G., Eds.) pp 396−398, OEMF spa, Milan, Italy.

3. Greenblatt, M. S., Bennett, W. P., Hollstein, M., and Harris, C. C. (1994) Mutations in the p53 tumor suppressor gene:  clues to cancer etiology and molecular pathogenesis.Cancer Res.54, 4855−4878.

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