Asymmetric Chemoenzymatic Synthesis of Miconazole and Econazole Enantiomers. The Importance of Chirality in Their Biological Evaluation
Author:
Affiliation:
1. Departamento de Química Orgánica e Inorgánica, Instituto Universitario de Biotecnología de Asturias, Universidad de Oviedo, 33006 Oviedo, Spain
2. Centro Nacional de Biotecnología del CSIC, Darwin 3, 28049 Cantoblanco, Madrid, Spain
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo102459w
Reference39 articles.
1. Analysis of the reactions used for the preparation of drug candidate molecules
2. The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously
3. Pharmacologically active compounds in the environment and their chirality
4. Synthesis of Chiral Drug Substances
5. Miconazole in the Treatment of Coccidioidomycosis
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