Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore-Reference-Cited by-同舟云学术

Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore

Published:2007-01-31 Issue:4 Volume:50 Page:595-598
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gemma Sandra¹,Campiani Giuseppe¹,Butini Stefania¹,Kukreja Gagan¹,Joshi Bhupendra P.¹,Persico Marco¹,Catalanotti Bruno¹,Novellino Ettore¹,Fattorusso Ernesto¹,Nacci Vito¹,Savini Luisa¹,Taramelli Donatella¹,Basilico Nicoletta¹,Morace Giulia¹,Yardley Vanessa¹,Fattorusso Caterina¹

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico and European Research Centre for Drug Discovery and Development, Universita' di Siena, via Aldo Moro, 53100 Siena, Italy, Dipartimento di Chimica delle Sostanze Naturali and Dipartimento di Chimica Farmaceutica e Tossicologica Universita' di Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy, Dipartimento di Sanita' Pubblica-Microbiologia-Virologia, Universita' di Milano, Via Pascal 36, 20133 Milano, Italy, and Department of Infectious and Tropical...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm061429p

Reference12 articles.

1. Antimalarial drug resistance

2. Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum

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