Virtual Screening Identification of Nonfolate Compounds, Including a CNS Drug, as Antiparasitic Agents Inhibiting Pteridine Reductase-Reference-Cited by-同舟云学术

Virtual Screening Identification of Nonfolate Compounds, Including a CNS Drug, as Antiparasitic Agents Inhibiting Pteridine Reductase

Published:2010-12-02 Issue:1 Volume:54 Page:211-221
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ferrari Stefania¹,Morandi Federica¹,Motiejunas Domantas¹,Nerini Erika¹²,Henrich Stefan²,Luciani Rosaria¹,Venturelli Alberto¹,Lazzari Sandra¹,Calò Samuele¹,Gupta Shreedhara³,Hannaert Veronique³,Michels Paul A. M.³,Wade Rebecca C.²,Costi M. Paola¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy

2. Heidelberg Institute for Theoretical Studies (HITS) gGmbH, Schloss-Wolfsbrunnenweg 35, 69118 Heidelberg, Germany

3. Research Unit for Tropical Diseases, de Duve Institute and Laboratory of Biochemistry, Université catholique de Louvain, Avenue Hippocrate 74, B-1200 Brussels, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1010572

Reference51 articles.

1. Short‐Course of Oral Miltefosine for Treatment of Visceral Leishmaniasis

2. Antimicrobial Dihydrofolate Reductase Inhibitors - Achievements and Future Options: Review

3. Anticancer Antifolates: Current Status and Future Directions

4. Mechanisms of Resistance of Malaria Parasites to Antifolates

5. The Roles of Pteridine Reductase 1 and Dihydrofolate Reductase-Thymidylate Synthase in Pteridine Metabolism in the Protozoan Parasite Leishmania major

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