A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields-Reference-Cited by-同舟云学术

A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields

Published:2011-02-22 Issue:6 Volume:54 Page:1740-1751
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Broccatelli Fabio¹,Carosati Emanuele¹,Neri Annalisa²,Frosini Maria²,Goracci Laura³,Oprea Tudor I.⁴,Cruciani Gabriele¹

Affiliation:

1. Laboratory of Chemometrics, Department of Chemistry, University of Perugia, Via Elce di Sotto 10, I-06123 Perugia, Italy

2. Department of Neuroscience, Pharmacology Unit, University of Siena, Siena, Italy

3. Molecular Discovery Limited, 215 Marsh Road, Pinner, Middlesex, London HA5 5NE, United Kingdom

4. Division of Biocomputing, Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, MSC11 6145, Albuquerque, New Mexico 87131, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101421d

Reference119 articles.

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2. Mannhold, R.; Kubinyi, H.; Folkers, G.InAntitargets: Prediction and Prevention of Drug Side Effects;Vaz, R. J., Klabunde, T., Eds.Wiley-VCH:Weinheim, 2008; ppXXI−XX.

3. The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay

4. Effects of Drug Transporters on Volume of Distribution

5. The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

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