Stereoselective Synthesis of a MCHr1 Antagonist-Reference-Cited by-同舟云学术

Stereoselective Synthesis of a MCHr1 Antagonist

Published:2007-11-13 Issue:25 Volume:72 Page:9648-9655
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Andersen Denise¹,Storz Thomas¹,Liu Pingli¹,Wang Xin¹,Li Leping¹,Fan Pingchen¹,Chen Xiaoqi¹,Allgeier Alan¹,Burgos Alain¹,Tedrow Jason¹,Baum Jean¹,Chen Ying¹,Crockett Rich¹,Huang Liang¹,Syed Rashid¹,Larsen Robert D.¹,Martinelli Mike¹

Affiliation:

1. Chemistry Process Research and Development, Amgen Inc., Thousand Oaks, California 19320, Medicinal Chemistry, Amgen SF, South San Francisco, California 94080, Process Chemistry, Incycte Corporation, Wilmington, Delaware 19880, and Pharmaceutical Products PPG-Sipsy, Z.I. La Croix Cadeau B.P. 79, F-49242 Avrillé Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo701894v

Reference38 articles.

1. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1

2. Molecular characterization of the melanin-concentrating-hormone receptor

3. Chronic intracerebroventricular infusion of MCH causes obesity in mice

4. Characterization of MCH-mediated obesity in mice

5. Melanin-Concentrating Hormone (MCH) Suppresses Thyroid Stimulating Hormone (TSH) release, in Vivo and in Vitro, via the Hypothalamus and the Pituitary

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