1. Department of Chemistry, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, Zhengzhou University, Zhengzhou, 450052, P. R. China, and School of Biomedical Sciences, Engineenring Research Center of Molecular Medicine of Chinese Education Ministry, Xiamen Key Laboratory of Ocean and Gene Drugs, Institute of Molecular Medicine of Huaqiao University, Fujian, Xiamen, 361021, P. R. China