Competition between mobile genetic elements drives optimization of a phage-encoded CRISPR-Cas system: insights from a natural arms race
Author:
Affiliation:
1. Department of Plant and Microbial Biology, University of California, 111 Koshland Hall, Berkeley, CA 94720, USA
2. International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
3. Chan Zuckerberg Biohub, San Francisco, CA 94158, USA
Abstract
Funder
National Institute of Allergy and Infectious Diseases
Chan Zuckerberg Biohub
Publisher
The Royal Society
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology
Link
https://royalsocietypublishing.org/doi/pdf/10.1098/rstb.2018.0089
Reference44 articles.
1. Deciphering the virus-to-prokaryote ratio (VPR): insights into virus-host relationships in a variety of ecosystems
2. Remarkable Mechanisms in Microbes to Resist Phage Infections
3. The Biology of CRISPR-Cas: Backward and Forward
4. CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
5. Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system
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