Fundamental limitations of network reconstruction from temporal data

Author:

Angulo Marco Tulio1ORCID,Moreno Jaime A.2,Lippner Gabor3,Barabási Albert-László456,Liu Yang-Yu578ORCID

Affiliation:

1. Institute of Mathematics, Universidad Nacional Autónoma de México, Juriquilla 76230, México

2. Institute of Engineering, Universidad Nacional Autónoma de México, CdMx 04510, México

3. Department of Mathematics, Northeastern University, Boston MA 02115, USA

4. Center for Complex Networks Research, Northeastern University, Boston MA 02115, USA

5. Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA

6. Center for Network Science, Central European University, Budapest 1052, Hungary

7. Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA

8. Harvard Medical School, Boston, MA 02115, USA

Abstract

Inferring properties of the interaction matrix that characterizes how nodes in a networked system directly interact with each other is a well-known network reconstruction problem. Despite a decade of extensive studies, network reconstruction remains an outstanding challenge. The fundamental limitations governing which properties of the interaction matrix (e.g. adjacency pattern, sign pattern or degree sequence) can be inferred from given temporal data of individual nodes remain unknown. Here, we rigorously derive the necessary conditions to reconstruct any property of the interaction matrix. Counterintuitively, we find that reconstructing any property of the interaction matrix is generically as difficult as reconstructing the interaction matrix itself, requiring equally informative temporal data. Revealing these fundamental limitations sheds light on the design of better network reconstruction algorithms that offer practical improvements over existing methods.

Funder

CONACyT postdoctoral

John Templeton Foundation

European Commission

Publisher

The Royal Society

Subject

Biomedical Engineering,Biochemistry,Biomaterials,Bioengineering,Biophysics,Biotechnology

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