Affiliation:
1. University of Virginia, 480 Ray C. Hunt Dr., Charlottesville, VA 22903, USA
Abstract
Essentially all living systems produce complex carbohydrates as an energy source, structural component, protective coat or adhesive for cell attachment. Many polysaccharides are displayed on the cell surface or are threaded through proteinaceous tunnels for degradation. Dictated by their chemical composition and mode of polymerization, the physical properties of complex carbohydrates differ substantially, from amphipathic water-insoluble polymers to highly hydrated hydrogel-forming macromolecules. Accordingly, diverse recognition and translocation mechanisms evolved to transport polysaccharides to their final destinations. This review will summarize and compare diverse polysaccharide transport mechanisms implicated in the biosynthesis and degradation of cell surface polymers in pro- and eukaryotes.
Funder
U.S. Department of Energy
National Institute of General Medical Sciences
Subject
Biomedical Engineering,Biomaterials,Biochemistry,Bioengineering,Biophysics,Biotechnology
Cited by
11 articles.
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