Flagellar kinematics reveals the role of environment in shaping sperm motility-Reference-Cited by-同舟云学术

Flagellar kinematics reveals the role of environment in shaping sperm motility

Published:2020-09 Issue:170 Volume:17 Page:20200525
ISSN:1742-5689
Container-title:Journal of The Royal Society Interface
language:en
Short-container-title:J. R. Soc. Interface.

Author:

Guasto Jeffrey S.¹^ORCID,Estrada Jonathan B.²³^ORCID,Menolascina Filippo⁴⁵,Burton Lisa J.⁶,Patel Mohak³,Franck Christian³,Hosoi A. E.⁶,Zimmer Richard K.⁷⁸,Stocker Roman⁹¹⁰^ORCID

Affiliation:

1. Department of Mechanical Engineering, Tufts University, Medford, MA 02155, USA

2. Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA

3. School of Engineering, Brown University, Providence, RI 02912, USA

4. School of Engineering, Institute for Bioengineering, University of Edinburgh, King's Buildings, EH9 3BF Edinburgh, UK

5. Synthsy – Centre for Systems and Synthetic Biology, University of Edinburgh, King's Buildings, EH9 3BF Edinburgh, UK

6. Department of Mechanical Engineering, MIT, Cambridge, MA 02139, USA

7. Department of Ecology and Evolutionary Biology, UCLA, Los Angeles, CA 90095, USA

8. School of Biological Sciences, University of Queensland, St Lucia, Brisbane 4072, Queensland, Australia

9. Ralph M. Parsons Laboratory, Department of Civil and Environmental Engineering, MIT, Cambridge, MA 02139, USA

10. Institute of Environmental Engineering, Department of Civil, Environmental and Geomatic Engineering, ETH Zurich, 8093 Zurich, Switzerland

Abstract

Swimming spermatozoa from diverse organisms often have very similar morphologies, yet different motilities as a result of differences in the flagellar waveforms used for propulsion. The origin of these differences has remained largely unknown. Using high-speed video microscopy and mathematical analysis of flagellar shape dynamics, we quantitatively compare sperm flagellar waveforms from marine invertebrates to humans by means of a novel phylokinematic tree. This new approach revealed that genetically dissimilar sperm can exhibit strikingly similar flagellar waveforms and identifies two dominant flagellar waveforms among the deuterostomes studied here, corresponding to internal and external fertilizers. The phylokinematic tree shows marked discordance from the phylogenetic tree, indicating that physical properties of the fluid environment, more than genetic relatedness, act as an important selective pressure in shaping the evolution of sperm motility. More broadly, this work provides a physical axis to complement morphological and genetic studies to understand evolutionary relationships.

Funder

University of California, Los Angeles

Division of Ocean Sciences

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Gordon and Betty Moore Foundation

Division of Integrative Organismal Systems

Publisher

The Royal Society

Subject

Biomedical Engineering,Biochemistry,Biomaterials,Bioengineering,Biophysics,Biotechnology

Link

https://royalsocietypublishing.org/doi/pdf/10.1098/rsif.2020.0525