Chemical Profile by Gas Chromatography/Mass Spectrometry of Ethyl Acetate and N-butanol Extracts of Centaurea tougourensis Boiss. & Reut

Author:

Bensaad Mohamed Sabri1,Dassamiour Saliha2,Hambaba Leila2,Kahoul Mohamed Amine3,Sami Rokayya4,Al Masoudi Luluah M.5,Al-Mushhin Amina A. M.6,Benajiba Nada7

Affiliation:

1. Laboratory of Cellular and Molecular Physio-Toxicology-Pathology and Biomolecules (LPTPCMB), Faculty of Natural and Life Sciences, University Batna 2, 05000, Algeria

2. Laboratory of Biotechnology of Bioactive Molecules and Cellular Physiopathology (LBMBPC), Faculty of Natural and Life Sciences, University Batna 2, 05000, Algeria

3. Laboratory of Food Sciences (LSA), Institute of Agriculture and Veterinary Sciences, University Batna 1, 05000, Algeria

4. Department of Food Science and Nutrition, College of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

5. Department of Biology, Faculty of Sciences, Taif University, Taif 21944, Saudi Arabia

6. Department of Biology, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia

7. Department of Basic Health Sciences, Deanship of Preparatory Year, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

Abstract

Nowadays, plants bioactive compounds are considered as a new source of therapy, especially for the elaboration process of more effective drugs. 80% of the actual drug substances are purely natural and originate from plants, representing a new hope, especially for the treatment of chronic illnesses. The aim of this study is to characterize the phytochemical composition of C. tougourensis via gas chromatography-mass spectrometry (GC-MS) approach. This method allowed the identification of 45 compounds in the n-butanol extract (n-BuOH), in which 12 compounds were in majority, namely; 2H-Furo [2,3-b] indole, 3,3a,8,8atetrahydro-2,3-dimethyl- (16.12%), Benz [c] pyran-1,3-dione, 4,4-dimethyl- (14.87%), Octadecanoic acid,9-oxo-, methyl ester (9.69%), Hydromorphone (7.94%), Acetamide, N-[3-[2-(2,3-dihydro-3-hydroxy-2-oxo-3-indolyl)-1-oxoethyl]p (6.14%), 2,6-Di-n-propyl-4-(2-furyl)pyridine (6.11%), Norhydrocodone (5.98%), Anthracene, 1,2,3,4,5,6,7,8-octahydro- (4.72%), 2,4,6-Trimethylbenzonitrile, N-oxide (4.47%), 3-O-Methyl-d-glucose (2.94%), 3,5-Diethyl-4-(2-furyl) pyridine (2.75%) and 3H-Pyrrolo [3,2-f] quinoline, 5-methoxy-1,2,7,9-tetramethyl- (2.30%). Concerning the ethyl acetate (EA) extract; 23 compounds were identified, in which 13 compounds were in majority, namely; [Bi-1,4-cyclohexadien-1-yl]-3,3,′6,6′-tetrone, 4,4′-dihydroxy-2,2,′5,5′-tetramethyl- (27.31%), Thiosulfuric acid, S-(2-aminoethyl) ester (15.07%), 2-Pentadecanone, 6,10,14-trimethyl- (8.91%), 3-Methyl-4-(phenylthio)-2-prop-2-enyl-2,5-dihydrothiophene 1,1-dioxide (7.12%), Tetrapentacontane, 1,54-dibromo- (5.74%), Heptacos-1-ene (5.03%), Propionic acid, 3-iodo-, tetradecyl ester (4.92%), 2-Methyl-E-7-octadecene (4.68%), 7,8-Epoxylanostan-11-ol, 3-acetoxy- (3.65%), 4-Fluoro-1-methyl-5-carboxylic acid, ethyl(ester) (3.15%), Tetrapentacontane, 1,54-dibromo- (2.79%), Undec-10-ynoic acid, tetradecyl ester (2.77%), 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (2.72%).

Publisher

American Scientific Publishers

Subject

Renewable Energy, Sustainability and the Environment,Biomaterials,Bioengineering

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