Author:
Matushevskaya E. V.,Svyrzhevskaya E. V.
Abstract
The data of foreign and domestic clinical studies on the efficacy and safety of sertaconazole (SK)is discussed. Broad spectrum of activity of SK and lack of resistance to the drug is established. Several studies opens new opportunities for the SK for the treatment of dermatosis, in the pathogenesis of which play an important role of opportunistic infection. High efficiency and compliance, a significantly greater safety index than that of the other members of the azole group, suggest the SK as a formulation that extends the capabilities of the outer antimycotic therapy of fungal infections of the skin.
Publisher
Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov
Reference24 articles.
1. Piraccini B.M., Gianni C. Update on the management of onychomycosis. G Ital Dermatol Venereol. 2013 Dec; 148 (6): 633-8.
2. Agut J. et al. Direct membrane damaging effect of Sertaconazole on Candida albicans as a mechanism of its fun_gicidal activity. Arzneim. Forsch. Drug Res. 1992; 42: 721-724.
3. Farre M., Ugena B., Badenas J.M. et al. Pharmacokineticsand tolerance of sertaconazole in man after repeated percutaneous admin-istration.Arzneimittelforschung. 1992; 42: 752-754.
4. Carrillo-Munoz A.J., Tur-Tur C., Cardenes D.C., Estivill D., Giusiano G. Sertaconazole nitrate-shows fungicidal and fungistatic activities against Trichophytonrubrum, Trichophyton mentagrophytes, and Epidermophyton loccosum, causative agent soft in eapedis. Antimicrob Agents Chemother. 2011; 55 (9): 4420-4431.
5. Сarrilo-Muñoz A.J., Tur C., Torres J. In-vitro antifungal activity of sertaconazole, bifonazole, ketoconazole, and miconazole against yeasts of the Candida genus. J Antimicrob Chemother. 1996; 37 (4): 815-819.
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