Author:
Carrillo-Muñoz Alfonso J.,Tur-Tur Cristina,Cárdenes Delia C.,Estivill Dolors,Giusiano Gustavo
Abstract
ABSTRACTThe fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis,Trichophyton rubrum,Trichophyton mentagrophytes, andEpidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 μg/ml, respectively, although values were higher forT. mentagrophytesthan for the others. This is the first comprehensive demonstration of the fungicidal activity of sertaconazole against dermatophytes.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
20 articles.
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