Diastereoselective synthesis of 3-[2-chloro(bromo)phenyl]2-methyl-2-[(prop-2-in-1-yl)oxy]oxiranes and 5-[3-chloro(bromo)phenyl]-2,2,4-trimethyl-4-[(prop-2-in-1-yl)]1,3-dioxolane

Abstract

The interaction of halogen-substituted benzaldehydes with 3-(1-chloroethoxy)prop-1-yne leads to the formation of unsaturated ethers of 2-hydroxyoxirane. The formation of the latter was confirmed by the reaction of the latter with acetone in the presence of BF3·Et2O with the formation of substituted 1,3-dioxolanes.