Affiliation:
1. Institute of Biochemistry and Physiology of Plants and Microorganisms,
Saratov Scientific Centre of the Russian Academy of Sciences
2. Saratov State Vavilov Agrarian University
Abstract
With the growing number of cancers, new assistive tools are required to obtain extensive molecular profiles of patients to help identify the disease. Early diagnosis of cancer is based on the analysis of relevant biomarkers, which can be used to monitor the population in order to identify the disease until it can be determined using standard methods and is not clinically manifest. One of the potential markers of cancer is heat shock proteins that act as molecular chaperones. Changes in heat shock proteins expression can serve as an important diagnostic marker of the cell’s response to damage. The paper presents a brief overview of the prevalence of oncological diseases in the world, the need of early oncological diagnostics development, as well as the prospects for the use of heat shock proteins in making an oncological diagnosis.
Publisher
The Russian Academy of Sciences