mTOR pathway inhibitors in cancer therapy: moving past rapamycin
Author:
Affiliation:
1. Department of Clinical Pharmacology, Section of Experimental Oncology/Molecular Pharmacology, Medical University of Vienna, Vienna, Austria.
Publisher
Future Medicine Ltd
Subject
Pharmacology,Genetics,Molecular Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/pgs.10.113
Reference12 articles.
1. Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy
2. Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony
3. The Pharmacology of mTOR Inhibition
4. Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
5. Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E
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