Genetics and adverse events with irinotecan treatment: what do we know?
Author:
Affiliation:
1. Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
2. CIBERER U-705, Barcelona, Spain
Publisher
Future Medicine Ltd
Subject
Pharmacology,Genetics,Molecular Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/pgs-2019-0012
Reference21 articles.
1. Bevacizumab in Combination With Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study
2. Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer
3. Irinotecan Combined With Bolus Fluorouracil, Continuous Infusion Fluorouracil, and High-Dose Leucovorin Every Two Weeks (LV5FU2 Regimen): A Clinical Dose-Finding and Pharmacokinetic Study in Patients With Pretreated Metastatic Colorectal Cancer
4. Phase III Comparison of Two Irinotecan Dosing Regimens in Second-Line Therapy of Metastatic Colorectal Cancer
5. UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer
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1. Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan;Food and Chemical Toxicology;2023-12
2. PharmFrag: An Easy and Fast Multiplex Pharmacogenetics Assay to Simultaneously Analyze 9 Genetic Polymorphisms Involved in Response Variability of Anticancer Drugs;International Journal of Molecular Sciences;2020-12-17
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