Managing recalcitrant hypercholesterolemia in patients on current best standard of care: efficacy and safety of novel pharmacotherapies

Author:

Sahebkar Amirhossein12,Watts Gerald F3

Affiliation:

1. Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2. Cardiovascular Research Center, Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

3. Lipid Disorders Clinic, Cardiovascular Medicine, Royal Perth Hospital & Metabolic Research Centre, School of Medicine & Pharmacology, University of Western Australia, Perth, Australia

Publisher

Informa UK Limited

Subject

Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism

Reference75 articles.

1. Pischon T, Girman CJ, Sacks FM, Rifai N, Stampfer MJ, Rimm EB. Non-high-density lipoprotein cholesterol and apolipoprotein B in the prediction of coronary heart disease in men. Circulation 112(22), 3375–3383 (2005).

2. Watts GF, Gidding S, Wierzbicki AS et al. Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation. Int. J. Cardiol. 171(3), 309–325 (2014). •• A comprehensive review describing the latest guidelines for the identification and management of familial hypercholesterolemia (FH).

3. Nordestgaard BG, Chapman MJ, Humphries SE et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society. Eur. Heart J. 34(45), 3478–3490 (2013). •• A comprehensive review describing the latest guidelines for the identification and management of FH.

4. WHO. Familial hypercholesterolaemia: report of a WHO consultation. WHO, Paris, France (1997).

5. Fahed AC, Nemer GM. Familial hypercholesterolemia: the lipids or the genes? Nutr. Metab. (Lond.) 8(1), 23 (2011).

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