Emerging applications of stereotactic body radiotherapy

Author:

Lo Simon S1,Loblaw Andrew2,Chang Eric L3,Mayr Nina A4,Teh Bin S5,Huang Zhibin6,Yao Min1,Ellis Rodney J1,Biswas Tithi1,Sohn Jason W1,Machtay Mitchell1,Sahgal Arjun2

Affiliation:

1. Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, 11100 Euclid Avenue, LTR B181 Cleveland, OH 44106, USA

2. Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Science Centre, University of Toronto, Toronto, ON, Canada

3. Department of Radiation Oncology, University of Southern California, Los Angeles, CA, USA

4. Department of Radiation Oncology, University of Washington, Seattle, WA, USA

5. Department of Radiation Oncology, The Methodist Hospital, Cancer Center & Research Institute, Weill Cornell Medical College, Houston, TX, USA

6. Department of Radiation Oncology, East Carolina University, Greenville, NC, USA

Abstract

ABSTRACT:  Stereotactic body radiotherapy (SBRT) has been used extensively in patients with lung, liver and spinal tumors, and the treatment outcomes are very favorable. For certain conditions such as medically inoperable stage I non-small-cell lung cancer, liver and lung oligometastases, primary liver cancer and spinal metastases, SBRT is regarded as one of the standard therapies. In the recent years, the use of SBRT has been extended to other disease conditions and sites such as recurrent head and neck cancer, renal cell carcinoma, prostate cancer, adrenal metastasis, pancreatic cancer, gynecological malignancies, spinal cord compression, breast cancer, and stage II–III non-small-cell lung cancer. Preliminary data in the literature show promising results but the follow-up intervals are short for most studies. This paper will provide an overview of these emerging applications.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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