Author:
Pradiptama Yura,Purwanta Marijam,Notopuro Harianto
Abstract
Introduction: Streptococcus mutans is a gram-positive coccus commonly found in the human oral cavity and is a pathogen of dental caries. S. mutans known to form biofilm in infective endocarditis heart-valve. Fluoride usage known to reduce the risk of dental caries. This study aims to analyze how usage of fluoride in inhibiting S. mutans growth.Methods: This study was an experimental study. Antibacterial activity test was performed to evaluate the minimum inhibitory concentration (MIC) using dilution method of sodium fluoride. The minimum bactericidal concentration (MBC) was determined by culturing from the previous dilution test into Chocolate Agar Plate.Results: MIC for sodium fluoride is 4,8 mg/ml and the MBC for sodium fluoride to S. mutans is 4,8 mg/ml. We found S. mutans growth in higher concentration than 19,2 mg/ml. Conclusion: S. mutans was inhibited in dilution test. Growth of the bacteria in higher concentration of sodium fluoride is explained with quasi-irreversible inhibtior effects of fluorida.
Reference18 articles.
1. Jawetz E, Melnick J and Adelberg E. Medical Microbiology 24th ed. New York: McGraw-Hill, 2007.
2. Bowden GH. Mutans Streptococci caries and Chlorhexidine. Journal. 1996; 62: 700, 3-7.
3. Effect of Xylitol, Sodium Fluoride and Triclosan Containing Mouth Rinse on Streptococcus mutans;Subramaniam;Contemporary Clinical Dentistry,2011
4. Ryan KJ and Ray CG. Sherris Medical Microbiology 1st ed. New York: McGraw- Hill, 2004.
5. Marsh P. Dental Plaque as a Biofilm and a Microbial Community - implications for Health and Disease. BMC Oral Health. 2006; 6: S14.
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