Affiliation:
1. Universidade Federal de São Paulo, Brazil
Abstract
Cerebellar ataxias comprise a wide range of etiologies leading to central nervous system-related motor and non-motor symptoms. Recently, a large body of evidence has demonstrated a high frequency of non-motor manifestations in cerebellar ataxias, specially in autosomal dominant spinocerebellar ataxias (SCA). Among these non-motor dysfunctions, sleep disorders have been recognized, although still under or even misdiagnosed. In this review, we highlight the main sleep disorders related to cerebellar ataxias focusing on REM sleep behavior disorder (RBD), restless legs syndrome (RLS), periodic limb movement in sleep (PLMS), excessive daytime sleepiness (EDS), insomnia and sleep apnea.
Subject
Neurology,Neurology (clinical)
Reference31 articles.
1. Sleep disorders in neurodegenerative diseases;Raggi A;Eur J Neurol,2010
2. Non-movement disorder heralds symptoms of Machado Joseph disease years before ataxia;D'Abreu A;Mov Disord,2005
3. REM sleep behavior disorder;Frenette E;Med Clin North Am,2010
4. Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis;Schols L;Lancet Neurol,2004
5. Spinocerebellar ataxia type 1, 2 and 3 and restless legs syndrome: striatal dopamine D2 receptor status investigated by [11C]raclopride positron emission tomography;Reimold M;Mov Disord,2006
Cited by
69 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献