Affiliation:
1. Universidade Federal do Rio de Janeiro
2. Universidade Federal do Rio de Janeiro; Universidade Federal do Rio de Janeiro; Universidade Castelo Branco
Abstract
Electroencephalography (EEG) can be a valuable technique to assess electrophysiological changes related to dementia. In patients suspected of having dementia, the EEG is often quite informative. The sensitivity of the EEG to detect correlates of psychiatric disorders has been enhanced by means of quantitative methods of analysis (quantitative EEG). Quantitative features are extracted from, at least, 2 minutes of artifact-free, eyes closed, resting EEG, log-transformed to obtain Gaussianity, age-regressed, and Z-transformed relative to population norms (Neurometrics database). Using a subset of quantitative EEG (qEEG) features, forward stepwise discriminant analyses are used to construct classifier functions. Along this vein, the main objective of this experiment is to distinguish profiles of qEEG, which differentiate depressive from demented patients (n = 125). The results showed that demented patients present deviations above the control group in variables associated to slow rhythms: Normed Monopolar Relative Power Theta for Cz and Normed Bipolar Relative Power Theta for Head. On the other hand, the deviation below the control group occurs with the variable associated to alpha rhythm: Normed Monopolar Relative Power Alpha for P3, in dementia. Using this method, the present investigation demonstrated high discriminant accuracy in separating Primary Degenerative Dementia from Major Depressive Disorder (Depression).
Subject
Neurology,Neurology (clinical)
Reference28 articles.
1. Electroencephalogram of man;Berger H;Arch Psychiat Nervenkr,1937
2. EEG in clinical diagnosis and its relationship to other neurological tests in clinical electroencephalography and topographic Brain Mapping;Duffy FH,1989
3. Electroencephalography: basic principles, clinical applications and related fields;Brenner RP,1993
4. Psychiatric aspects of neurological diseases;Harner RN,1975
5. Quantitative, waking EEG research on depression;Pollock VE;Biol Psychiatry,1990
Cited by
27 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献