Affiliation:
1. Universidade Federal de São João del-Rei, Brazil
2. Instituto Federal de Educação, Brazil
3. Centro Federal de Educação Tecnológica de Minas Gerais, Brazil
Abstract
ABSTRACT Objective: To verify the COVID-19 clinical characteristics, associated comorbidities, and outcomes in adolescents. Data source: This is a systematic review study based on articles published between 2020 and 2022 in the United States National Library of Medicine - PubMed (MedLine), Virtual Health Library – VHL (LILACS), Science Direct, Web of Science, and Scopus (Elsevier) databases. The study was registered in the International Prospective Register of Systematic Reviews, under No. CRD42022309108. Data synthesis: A total of 1188 studies were identified. After applying the selection criteria, 13 articles were included. Prevalence was 25%; mild cases were predominant; and fever, cough, headache, anosmia, nasal congestion, and ageusia were frequent. Fever and cough were proportionally higher in hospitalized cases: 81 and 68%, respectively. Dyspnea (odds ratio [OR] 6.3; confidence interval 95%[CI] 2.8–14.3), fever (OR 3.8; 95%CI 2.0–7.4), and cough (OR 3.4; 95%CI 2.0–6.0) were associated with severe cases. Up to 28% required intensive care and 38% required mechanical ventilation. Pre-existing comorbidities increased the risk of hospitalization and death. Severe cases were associated with the risk of death (relative risk [RR] 4.6; 95%CI 2.8–7.5). The black, mixed, and indigenous races/skin colors represented risk groups, as well as residents of poorer regions. Conclusions: The review provided a better understanding of the disease profile and may favor the development of public policies, in addition to contributing to the current literature in the field of adolescent health.
Subject
Pediatrics, Perinatology and Child Health
Reference37 articles.
1. COVID-19 pandemic: from origins to outcomes. A comprehensive review of viral pathogenesis, clinical manifestations, diagnostic evaluation, and management;Ochani R;Infez Med,2021
2. COVID-19: a review on the novel coronavirus disease evolution, transmission, detection, control and prevention;Sharma A;Viruses,2021
3. SARS-CoV-2 infection in children;Lu X;N Engl J Med,2020
4. Ministério da Saúde. Secretaria de Vigilância em Saúde [homepage on the Internet]
5. Clinical-epidemiological profile of children and adolescents with COVID-19 in Ceará;Cavalcante AN;Rev Bras Saúde Matern Infant,2021
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献