Diagnosis of frontotemporal dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Author:

Souza Leonardo Cruz de1ORCID,Hosogi Mirna Lie2ORCID,Machado Thais Helena1ORCID,Carthery-Goulart Maria Teresa3ORCID,Yassuda Mônica Sanches4ORCID,Smid Jerusa2ORCID,Barbosa Breno José Alencar Pires5ORCID,Schilling Lucas Porcello6ORCID,Balthazar Marcio Luiz Figueredo7ORCID,Frota Norberto Anízio Ferreira8ORCID,Vale Francisco Assis Carvalho9ORCID,Caramelli Paulo1ORCID,Bertolucci Paulo Henrique Ferreira10ORCID,Chaves Márcia Lorena Fagundes11ORCID,Brucki Sonia Maria Dozzi2ORCID,Nitrini Ricardo2ORCID,Bahia Valéria Santoro12ORCID,Takada Leonel Tadao2ORCID

Affiliation:

1. Universidade Federal de Minas Gerais, Brasil; Universidade Federal de Minas Gerais, Brasil

2. Universidade de São Paulo, Brasil

3. Universidade de São Paulo, Brasil; Universidade Federal do ABC, Brasil

4. Universidade de São Paulo, Brasil; Universidade de São Paulo, Brasil

5. Universidade de São Paulo, Brasil; Universidade Federal de Pernambuco, Brasil; Instituto de Medicina Integral Prof. Fernando Figueira, Brasil

6. Pontifícia Universidade do Rio Grande do Sul, Brasil; Pontifícia Universidade do Rio Grande do Sul, Brasil; Pontifícia Universidade do Rio Grande do Sul, Brasil

7. Universidade Estadual de Campinas, Brasil

8. Hospital Geral de Fortaleza, Brasil; Universidade de Fortaleza, Brasil

9. Universidade Federal de São Carlos, Brasil

10. Universidade Federal de São Paulo, Brasil

11. Hospital de Clínicas de Porto Alegre, Brasil; Universidade Federal do Rio Grande do Sul, Brasil

12. Universidade Cidade de São Paulo, Brasil

Abstract

ABSTRACT “Frontotemporal dementia” (FTD) is a clinical syndrome characterized by the focal involvement of the frontal and/or temporal lobes. FTD has three clinical phenotypes: the behavioral variant and two linguistic subtypes, namely, non-fluent/agrammatic primary progressive aphasia (PPA-NF/A) and semantic PPA (PPA-S). FTD is the second most common cause of dementia in individuals under the age of 65 years. This article presents recommendations for the diagnosis of FTD in the Brazilian scenario, considering the three levels of complexity of the health system: primary health care, secondary and tertiary levels. Diagnostic guidelines are proposed, including cognitive testing, behavioral and language assessments, laboratory tests, and neuroimaging.

Publisher

FapUNIFESP (SciELO)

Subject

Cognitive Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Neurology,Sensory Systems

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