Duplication of the hypophysis associated with precocious puberty: presentation of two cases and review of pituitary embryogenesis

Author:

Penna Gustavo Cancela e1,Pimenta Márcia Porto2,Drummond Juliana B.2,Sarquis Marta3,Martins José Carlos T.4,Campos Rodrigo C. de5,Dias Eduardo Pimentel1

Affiliation:

1. Hospital Felício Rocho

2. Hospital Mater Dei

3. Universidade Federal de Minas Gerais

4. Axial Centro de Imagens

5. Hospital das Clínicas

Abstract

Pituitary duplication is a rare malformation commonly associated with other major neural/craniofacial anomalies, easily shown by magnetic resonance imaging. The authors describe two girls with duplication of the pituitary gland and thickening of the hypothalamus, facial dysmorphism and precocious pubertal development. The pathogenesis of pituitary duplication and its relationship with precocious pubertal development are discussed.

Publisher

FapUNIFESP (SciELO)

Subject

General Medicine,Endocrinology, Diabetes and Metabolism

Reference9 articles.

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2. Review of the embryologic development of the pituitary gland and report of a case of hypophyseal duplication detected by MRI;Kollias SS;Neuroradiology,1995

3. Duplication of pituitary gland;Shah S;J Comput Assist Tomogr,1997

4. Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal teratoma;Hamon-Kérautret M;Pediatr Radiol,1998

5. Epignathus teratoma: report of three cases with a review of the literature;Vandenhaute B;Cleft Palate Craniofac J,2000

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