The expression of an intraspecific aggressive reaction in the face of a stressor agent alters the immune response in rats

Author:

Barreto-Medeiros J. M.1,Feitoza E. G.1,Magalhães K.1,da Silva R. R.1,Manhães-de-Castro F. M.1,Manhães-de-Castro R.1,De-Castro C. M. M. B.1

Affiliation:

1. Universidade Federal de Pernambuco, Brazil

Abstract

The repercussion on the immune response of the expression of intraspecific aggressiveness in the face of a stressor agent was investigated in rats. Ninety-day-old animals were divided into three groups: the control group (only immunological measurements were performed), the foot-shock (FS) (animals individually receiving FS), and the intraspecific aggressive response (IAR) group (animals receiving FS and presenting IAR). For immunological measurements, blood samples were collected promptly at 7 and 15 days after FS or IAR. The FS reduced the total leukocyte amount presented. However, aggressiveness triggered not only reduction of the leukocytes, but also lymphocyte decrease and neutrophil increase. Moreover, an elevation in total leukocytes associated with an increase in the humoral immune response was also observed one week after IAR. In this study, the expression of intraspecific aggressiveness in the face of a stressor seemed to activate the immune system and to potentiate the antigen specific humoral response.

Publisher

FapUNIFESP (SciELO)

Subject

General Agricultural and Biological Sciences

Reference31 articles.

1. Action of selective serotonin reuptake inhibitor on aggressive behavior in adult rats submitted to the neonatal malnutrition;BARRETO MEDEIROS J. M.;Arq Neuropsiquiatr.,2001

2. Peptides and hormones shared by the neuroendocrine and immunologic systems;BLALOCK J. E.;J. Immunol.,1985

3. L'Encéphale;CASTELNAU E. T.;Revue de Psychiatrie Clinique Biologique et Thérapeutique,1993

4. Macrophage activation revisited;CELADA A.;Immunol. Today.,1994

5. Chronic social stress, social status, and susceptibility to upper respiratory infections in nonhuman primates;COHEN S.;Psychosom Med.,1997

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3