Could leprosy reaction episodes be exacerbated by oral infections?-Reference-Cited by-同舟云学术

Could leprosy reaction episodes be exacerbated by oral infections?

Published:2011-10 Issue:5 Volume:44 Page:633-635
ISSN:0037-8682
Container-title:Revista da Sociedade Brasileira de Medicina Tropical
language:
Short-container-title:Rev. Soc. Bras. Med. Trop.

Author:

Motta Ana Carolina Fragoso¹,Furini Renata Bazan²,Simão João Carlos Lopes²,Vieira Mariana Bellini²,Ferreira Maria Aparecida Nunes²,Komesu Marilena Chinali¹,Foss Norma Tiraboschi²

Affiliation:

1. University of São Paulo

2. University of São Ribeirão Preto

Abstract

INTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection. METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection. RESULTS: Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups. CONCLUSIONS: Oral infection could be an exacerbating factor in leprosy reactions.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,Microbiology (medical),Parasitology

Link

http://www.scielo.br/pdf/rsbmt/v44n5/22.pdf

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