Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

Author:

Benatto Mariana Tedeschi1,Florencio Lidiane Lima1,Carvalho Gabriela Ferreira1,Dach Fabíola1,Bigal Marcelo Eduardo2,Chaves Thaís Cristina1,Bevilaqua-Grossi Débora3

Affiliation:

1. Universidade de São Paulo, Brasil

2. Teva Pharmaceutical Industries Ltd, EUA

3. Universidade de São Paulo, Brasil; Universidade de São Paulo, Brasil

Abstract

ABSTRACT Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital. The 12-item Allodynia Symptom Checklist/Brazil questionnaire was applied to classify subjects according to the presence and severity of cutaneous allodynia. Results Cutaneous allodynia was identified in 81.3% of the episodic migraine group and 92.5% of the chronic migraine group (p = 0.03). No increased association could be attributed to chronic migraine when adjusted by years with disease (PR = 1.12; 95%CI = 0.99 to 1.27; p = 0.06). The groups also did not differ in the severity of allodynia, and severe presentation was the most frequent. Discussion Both groups seemed to be similarly affected in the cephalic and extracephalic regions, with the same severity. Conclusion Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Reference22 articles.

1. The epidemiology of primary headache disorders;Robbins MS;Semin Neurol,2010

2. Chronic migraine: definition, epidemiology, risk factors and treatment;Carod-Artal FJ;Rev Neurol,2012

3. The International Classification of Headache Disorders;Cephalalgia,2013

4. Prevalence and characteristics of allodynia in headache sufferers: a population study;Bigal ME;Neurology,2008

5. A comparison of migraine patients with and without allodynia symptoms;Kalita J;Clin J Pain,2009

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